MOSCOW, March 21 (Reuters) - Russia said on Friday that U.S. sanctions imposed over the annexation of Crimea would not serve American interests and would elicit a tough response, harming bilateral ties.
"We ... will be tough in our response," the Russian Foreign Ministry said in a statement.
"Washington should be under no illusions: The effectiveness of its sanctions in terms of American interests is zero. But the harm to U.S.-Russian relations due to these irresponsible actions is inevitable." (Reporting by Alissa de Carbonnel; Editing by Steve Gutterman)