Liberia says U.S. authorities OK use of experimental Ebola drug

by Reuters
Tuesday, 12 August 2014 00:25 GMT

(Adds comment from U.S. Heath and Human Services department, details, background)

By Clair MacDougall and Daniel Flynn

MONROVIA/DAKAR Aug 11 (Reuters) - U.S. authorities have approved a request from Liberia's government to send sample doses of the experimental ZMapp drug to treat Liberian doctors infected with Ebola, the Liberian presidency said.

A statement on the Liberian presidency's website said the drug would be delivered to the West African country this week by a U.S. government representative, after a direct appeal to President Barack Obama on Friday by Liberian President Ellen Johnson Sirleaf.

However, a spokesperson for the U.S. Health and Human Services (HHS) Department said U.S. authorities had simply assisted in connecting the Liberian government with the drug's manufacturer.

ZMapp, produced by California-based Mapp Biopharmaceutical, has already been used to treat two U.S. aid workers and a Spanish priest infected with Ebola.

"Since the drug was shipped for use outside the U.S., appropriate export procedures had to be followed," the HHS spokesperson said, adding the drug company had worked directly with the Liberian government.

The death toll from the world's worst outbreak of Ebola has climbed to 1,013 people, according to figures on Monday from the World Health Organization, which has branded the outbreak an international health emergency.

The Liberian statement said the head of the WHO, Margaret Chan, had authorized the dispatch of additional doses of the experimental drug to Liberia to support the treatment of affected doctors. Those doses will be delivered by a WHO expert this week.

A WHO spokesman did not immediately respond to requests for comment.

The two U.S. aid workers treated with ZMapp, who contracted Ebola in Liberia, have since shown some signs of improvement. They are now in a hospital in Atlanta, Georgia, after being medically evacuated.

Spain on Sunday also authorised the use of the ZMapp on 75-year-old Spanish priest Miguel Pajares - the first European infected in the outbreak - who was evacuated to Madrid last week after contracting the haemorrhagic fever while working in a Monrovia hospital.

Liberian Information Minister Lewis Brown told Reuters that it was not clear how many doses of the drug had been sent but it could be in Monrovia within the next 48 hours.

The WHO has said the epidemic will likely continue for months as the region's healthcare systems struggle to cope and has appealed urgently for funding and emergency medical staff.

A WHO medical ethics committee had discussed on Monday the use of experimental drugs to tackle the world's worst outbreak of the deadly virus. It is due to announce its findings on Tuesday.

Aside from the ethics of using experimental drugs in humans, the committee was also due to consider who should receive priority for the limited supplies of the drugs. (Additional reporting by Michele Gershberg; Editing by Ken Wills)

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Liberia says U.S. authorities OK use of experimental Ebola drug

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